PEOPLE
Dennis Fisher
PRINCIPAL
Dennis M. Fisher, MD

I started P < while a Professor of Anesthesia and Pediatrics at the University of California San Francisco. Subsequently, I was Vice President of Medical Affairs for the DURECT Corporation, a pharmaceutical company developing extended-release drug products. In 2003, I resumed full-time consulting through P <.

EDUCATION

  • 1968-1972: Massachusetts Institute of Technology, Bachelor of Science
  • 1971-1972: Massachusetts Institute of Technology, Masters in City Planning (Health Planning)
  • 1972-1976: Yale University, Doctor of Medicine

    • MEDICAL TRAINING

  • 1976-1978: Childrens Hospital of Philadelphia, Residency in Pediatrics
  • 1978-1980: Hospital of the University of Pennsylvania, Residency in Anesthesia
  • 1980: Childrens Hospital of Philadelphia, Fellowship in Pediatric Critical Care

    • RESEARCH TRAINING

  • 1980-1981: University of California San Francisco, Fellowship in Clinical Pharmacology/Pharmacokinetics

    • EMPLOYMENT

  • 1981-2000: Professor of Anesthesia and Pediatrics at the University of California San Francisco. I performed numerous phase I-IV clinical trials, conducted independent research funded by the National Institutes of Health, and assisted the Food and Drug Administration (as a reviewer for both primary and secondary NDA's and as a member of special committees). I also reviewed grants for the National Institutes of Health and other organizations, tutored the Sheiner/Beal NONMEM course and the Rowland / Sheiner Workshop on Advanced Methods in Pharmacokinetics and Pharmacodynamics, and was a member of the Editorial Board of the journal Anesthesiology.

  • 2000-2003: Vice President of Medical Affairs and Medical Director, DURECT Corporation, Cupertino, California. I was the sole physician in a startup pharmaceutical company that focussed on the development of extended-release products using Alza's DUROS technology and the SABER technology developed by Southern Biosystems (a DURECT subsidiary).

  • 2003-present: Full-time consulting via P <

    • CURRICULUM VITAE (pdf format)

    Scott Brittain
    COLLABORATOR
    Scott Brittain, PhD

    Dr. Brittain started his consulting firm, PharmacoExcellence in 2017. He has collaborated with Dr. Fisher on a number of projects over the previous decade. Prior to starting PharmacoExcellence, he headed Clinical Research and Human Pharmacology at Supernus Pharmaceuticals. He joined Supernus in 2005, initially in Bioanalysis, then Clinical Pharmacokinetics and Pharmacokinetic and Pharmacodynamic Modeling and Simulation. Before entering the pharmaceutical industry, he taught chemistry at Georgia College and State University. He earned a Doctorate in Chemistry from Harvard University and a Bachelor of Science in Chemistry from the University of Alabama. Dr. Brittain has extensive experience in phase 1-3 clinical trial design and execution and evaluation in support of products in epilepsy and ADHD.

    EDUCATION

    • 1987-1995: University of Alabama, Chemistry, BS
    • 1995-2000: Harvard University, Physical Chemistry, PhD

    EMPLOYMENT

    • 2000-2003: Georgia College and State University, Assistant Professor of Chemistry
    • 2003-2005: Eno River Labs, Bioanalytical Sciences.
    • 2005-2009: Supernus Pharmaceuticals, Analytical Sciences.
    • 2009-2017: Supernus Pharmaceuticals, Clinical Pharmacokinetics.
    • 2014-2017: Supernus Pharmaceuticals, Clinical Research and Human Pharmacology.
    • 2017-present: PharmacoExcellence, LLC
    William Kramer
    AFFILIATE
    William G. Kramer, PhD

    Dr. Kramer and Dr. Fisher have collaborated on countless projects since 2003. With over 40 years of experience in the pharmaceutical industry and academic research, Dr. Kramer is an expert in clinical pharmacology, pharmacokinetics and pharmacodynamics, and assists client companies in program design, protocol preparation, study implementation, and the analysis and interpretation of results.

    EDUCATION

    • 1966-1971: University of Pittsburgh, Bachelor of Science in Pharmacy
    • 1971-1976: Ohio State University, Ph.D. in Pharmaceutics

    RESEARCH

    • University of Houston College of Pharmacy, Teacher and Clinical Pharmacokinetic Researcher

    EMPLOYMENT

    • 1986-1989: Schering-Plough Corporation, Department of Drug Metabolism and Pharmacokinetics
    • 1989-1997: Boehringer Mannheim, Director, Clinical Research; Head, Pharmacokinetics and Bioanalytics
    • 1997-2000: Quintiles Consulting, Senior Consultant
    • 2000-present: Kramer Consulting LLC, Principal Member